Friday, April 24, 2020

Why is a virus innocent until proven guilty?

Here is the text of some e-mails that I just sent.

To my college roommate who is an oncologist:

I hope you won't mind me asking you a question.

This pandemic has gotten me interested in the mechanics of viral transmission. I've been reading with great interest about the research of Lydia Bourouiba at MIT.  She has demonstrated with mathematical models, in peer reviewed research, that respiratory droplets travel much further than 6 feet, yet Anthony Fauci refuses to believe her -- when he's not a mechanical engineer.

In looking at the papers on viral transmission, there seems to be an assumption that viruses are not transmissible by aerosol until proven to be transmissible.  In the law, we would call this "innocent until proven guilty."  That's what we would call an issue of "burden of proof." Who has the burden of proving someone or something guilty? In the law, the burden is on the plaintiff or the prosecutor to prove the defendant guilty.

But why do we give the virus the benefit of the doubt? It seems to me, looking at news stories, that this assumption has gotten people in a lot of trouble both with Ebola and with this latest novel coronavirus.  Medical personnel went in with inadequate PPE and got sick... until they were in hazmat suits.

Why don't we assume that the virus is capable of aerosol transmission and even of penetrating the skin, until the virus is proven innocent?  The virus is not a human being with constitutional rights.  Why not guilty until proven innocent?

To the chair of the physics department of Dartmouth College

I got your name off the Dartmouth website as chair of the physics department.
I am an alum.  I majored in physics.  I was a TA in pre-med physics.   I have a question about the mechanics curriculum.
When I was in freshman physics, I remember quite vividly using a little spring loaded device that shot a steel ball.  We stopped the ball at several points and demonstrated that its arc of flight was a parabola.
I think we had the pre-med physics class doing that same experiment.

We didn't, as I recall, get into the mechanics of flight -- or aerodynamics.  That was deemed too complex, I believe, for pre-meds, who would struggle with the idea of a parabola.
Now, I'm seeing what I think are bad consequences of this curriculum decision.  Doctors assume that a round object, like a coronavirus, will fall like the steel ball within 6 feet. When Lydia Bourouiba of MIT does fluid mechanical modeling and demonstrates in a peer reviewed paper that respiratory droplets can travel up to  27 feet, due to turbulent flow, Anthony Fauci does not believe her.
To me, looking at the images of the coronavirus, given it's size and weight, it seems fairly clear that the little projections would make it capable of flight, like dandelion fluff -- at least for a while, until it dries up.   It's small and light, so it would not require big wings like a helicopter or an airplane, and not even as big of tendrils as dandelion fluff.

Yet doctors don't think that way.  They remember the steel ball falling along the parabola. They've made assumptions about the behavior of viruses in air that are unjustified, given fluid mechanics. They've repeatedly sent medical personnel into harm's way with inadequate PPE and those personnel have died as a result -- both in the Ebola situation and the COVID-19 situation.j



I am concluding that the pre-med physics curriculum needs to be drastically revised.  It is unlikely that a doctor would need to calculate the trajectory of a cannon ball, unlike Isaac Newton. It is much more likely that they would need to calculate the trajectory of something that can be blown about in air currents. 
To my sister-in-law who has a Ph.D. in mechanical engineering from CalTech.  This was a cover letter to forwarding the e-mail immediately above.

I am forwarding to you a copy of an e-mail that I just sent to the chair of the physics department at Dartmouth, where I went to college, about the curriculum of pre-med physics.
I'm remembering an interchange you and I had back when I was doing natural childbirth.  At that time, obstetricians were still doing episiotomies. This was a procedure where they would cut the tissue around the vagina during childbirth, on the belief that this would reduce tearing, or make tears easier to repair.
 It was your opinion, at the time, that this procedure was unjustified in view of mechanical engineering principles -- that the procedure would make tears worse, not better. I'm noticing that now, 30 years later, episiotomies have finally been discredited, though some doctors *still* do them.
I'm seeing something similar in the medical literature that I'm seeing about the transmission of coronavirus. They're making assumptions based on faulty understanding of fluid mechanics. 
I'm wondering if you've been following the research of Lydia Bourouiba at MIT -- and her modelling of the mechanics of flight of respiratory droplets -- and the rejection by Anthony Fauci of her conclusions.
I'm proposing to the chair of the physics department at Dartmouth that the curriculum of pre-med physics needs to be drastically revised.


*****

Here's another example of the virus being presumed innocent until proven guilty. This is in the question of whether pets can transmit the virus to humans.

 https://now.tufts.edu/articles/can-pets-get-or-spread-covid-19

Despite the fact that the virus is believed to have jumped from animals to humans in the first place, and the fact that infection in animals from humans has been documented, people don't believe the virus could still jump from animals to humans, because there is "no evidence."

Thursday, April 9, 2020

Fluid Dynamics and virus transmission

Here are some articles that I want to remember

https://www.usatoday.com/story/news/health/2020/03/30/coronavirus-social-distancing-mit-researcher-lydia-bourouiba-27-feet/5091526002/

Bourouiba models exhalation gas clouds and finds that they can travel up to 27 feet.  The CDC poo-poos this and says it's misleading.

In a Journal of the American Medical Association article published last week, Bourouiba said peak exhalation speeds can reach 33 to 100 feet per second and "currently used surgical and N95 masks are not tested for these potential characteristics of respiratory emissions."

Pottinger says that if the virus were effective at 27 feet more people would be sick. But we don't know how many people are sick. There are so many who are not being tested. This is a specious argument.

https://www.propublica.org/article/what-we-need-to-understand-about-asymptomatic-carriers-if-were-going-to-beat-coronavirus?fbclid=IwAR26XkDAb_EfR-SPnlu-v2_ilBD_05JzuxtRlupaat6fB4ccubCy-LLghJ4

https://medium.com/@jurgenthoelen/belgian-dutch-study-why-in-times-of-covid-19-you-can-not-walk-run-bike-close-to-each-other-a5df19c77d08

https://cee.mit.edu/people_individual/lydia-bourouiba/

Lindsey Marr https://www.nytimes.com/2020/06/12/well/live/Coronavirus-aerosols-linsey-marr.html

*******

Statement by one interlocutor

The Media has done exactly what it intended to do invoke FEAR in everyone.. I advise everyone to do your own research on the subject of viruses... this virus is not AIRBORNE!! Additionally, for those of you who think the masks are a shield here is another tidbit the size of the virus is so small it can easily goes through these masks... nothing other than a hazmat suit will protect you. Again, that is if its airborne.
I suggest that you ask our
Heavenly Father to give you clarity on this. I assure you He will.
For God has not given us the spirit of Fear but of power, and of love and of a sound mind
Timothy 1:7
Believe & Receive!

My response

There is an issue of wording here.  This virus is larger and heavier than, say, the measles virus.   The measles virus is considered "airborne" in the sense that it can rise, unaided, into the air and move freely about.

This virus is heavier than air and tends to want to fall on the ground.  It is believed to travel on respiratory droplets, not to be independently airborne, unlike the measles virus.

However, how far respiratory droplets can travel, how long they can stay airborne, and how far a virus can be effective on such a droplet is still a matter of active research.

This peer-reviewed study cosponsored by several prominent research institution found that the virus could be effective in the air on respiratory droplets for three hours.

https://www.nejm.org/doi/full/10.1056/NEJMc2004973

However, Lydia Bourouiba, an MIT researcher in fluid dynamics, has found that respiratory droplets can travel up to 27 feet. Fauci, who works for the CDC, which you so distrust, discounts this research as misleading, because he doesn't believe that the virus could be effective on droplets that travel so far.

https://www.usatoday.com/story/news/health/2020/03/30/coronavirus-social-distancing-mit-researcher-lydia-bourouiba-27-feet/5091526002/

In fact, the CDC and the WHO are conservative about how far the virus can travel in air.  Many researchers think it can go farther than what they say, as in the article that I cited above.

In the USA Today article, Pottinger is cited as saying that if the virus were effective at 27 feet more people would be sick.  But we don't know how many people are sick.  There are so many who are not being tested.  This is a specious argument.

Also, because the virus travels on droplets, which are larger than the virus -- its travel, upon exiting the mouth and nose, is limited. The masks are not to protect the wearer. The masks are to protect others.

*****

FB Discussion about Biden & War

One of my FB friends expressed puzzlement at how 15% of Bernie supporters said they would vote for Trump rather than Biden, given that Trump is so opposite Bernie when it comes to social welfare programs.  This was my response.

I know from having read the comments of Tulsi supporters, who were big peaceniks, like me, that their primary concern was Biden's hawkish record.  One thing that was cited to me was his strong support of cluster bombs, which often mutilate innocent children. This was a concern that many Trump supporters had with Hillary as well, that her record was hawkish. 

One thing that frustrated me with Tulsi's exclusion from the debates was how that kept the debates focused on domestic policy. The parochial myopia of many Americans with respect to our disastrous foreign policies, particularly with respect to military activities, is very disturbing.  Moreover, the Iron Triangle wants it that way.  They want everyone arguing about health care -- not about the kids we are killing in other countries, which is a profit center for big corporations.

Bernie was not just a socialist.  He was also anti-war. 

Many Trump supporters are anti-war as well. Some of them have been really disillusioned by his taking on military adventurism in Iran.  Anne Coulter said "We thought he was different, but he isn't different." I feel that this was a highly significant statement.

People who are opposed to Trump would do well to recognize that the way he has been attacked is not reaching the voters who support him. We need to look more intelligently at what groups we can lure away.

Nominating someone who vigorously supported cluster bombs was a mistake.

#Tulsi2020 #TulsiGabbard #JoeBiden #Biden #RegimeChangeWars #Hawks #Hawkish #Hawkishness

Tuesday, March 31, 2020

Is Hibiclens soap?

The question arose in a FB discussion as to whether Hibiclens would be effective in hand washing against the virus.  I wanted to memorialize our discussion.

The idea of soap is that it is a wetting agent.  It makes surfaces slippery.  This makes it easier to remove dirt -- including germs. Soap does also dissolve lipids.  Now what I need to check out is this stuff I've seen about virus coatings being lipids.

Skimming this article, it seems like at least SARS had a lipid bilayer with protein inside https://virologyj.biomedcentral.com/articles/10.1186/s12985-019-1182-0

This one says there's a lipid envelope for this virus
https://www.sciencedirect.com/topics/neuroscience/coronaviridae

This one says soap does break the lipid envelope
https://www.nytimes.com/2020/03/13/health/soap-coronavirus-handwashing-germs.html

I looked through the hibiclens website and they do not mention viruses

This is a Wikipedia article defining "soap" as a "salt of a fatty acid". In order to qualify it has to have an alkyl and a metal ion. https://en.m.wikipedia.org/wiki/Soap



This website has a list of ingredients for Hibiclens. I am not seeing one that matches the chemical description listed in Wikipedia.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4275eb53-1a7e-4a91-aac1-1085f40fac88

ACTIVE INGREDIENT
Chlorhexidine gluconate solution 4.0% w/v

INACTIVE INGREDIENTS
fragrance, gluconolactone, isopropyl alcohol 4% w/v, lauramine oxide, poloxamer 237, purified water and red 40

I now looked up these ingredients.

This is what I get when I search for lauramine oxide. It's a foaming agent, but it does not include a metal ion, therefore it is not a soap.
https://www.google.com/search?q=lauramine+oxide&ie=UTF-8&oe=UTF-8&hl=en-us&client=safari



This is an article about the active ingredient. Again there is no metal ion, so it is not a soap

https://en.m.wikipedia.org/wiki/Chlorhexidine



The other mysterious ingredient, is a surfactant, polaxamer or 237. These are non-ionic. They do not contain a metal ion. Therefore they are not a "soap."
https://en.m.wikipedia.org/wiki/Poloxamer



I have to conclude that Hibiclens is not a "soap."  It might foam like "soap," but that doesn't mean that it has the ability to dissolve lipids that soap has.

 I looked on their website, as I said above, and there is no mention of it being effective against viruses. I searched their help section for "virus" and found nothing. I feel the chemistry is very important here. Hibiclens may be a wetting agent, like soap, in that it makes things slippery; but, if it lacks the ionic form of soap, it probably lacks the ability to dissolve the lipid envelope around the virus. Ions are very important in the chemistry of dissolution.

Dissolving lipids is a key soap property that should help kill the virus.

More about lauramine oxide

https://ingredients.puracy.com/ingredient/lauramine-oxide

https://pubchem.ncbi.nlm.nih.gov/compound/Lauramine_oxide#section=Chemical-Vendors

Chemicals considered detergents

https://www.ncbi.nlm.nih.gov/sites/entrez?Db=pccompound&DbFrom=mesh&Cmd=Link&LinkName=mesh_pccompound&IdsFromResult=68003902 

Lauramine oxide is listed -- therefore it should have oil dissolving properties.

Meme about coronavirus

I don't know if this is valid.  I do not have a link from Johns Hopkins to this information. It does purport to be from Johns Hopkins, but one never knows. I have found a couple of other links.

A link

https://resources.finalsite.net/images/v1585609031/icsbudapestorg/sgbb89qwmfxmmammwurr/EvanParks_SeparatingFactsfromFiction_Covid-19-Facts.pdf

Another link


https://www.opednews.com/articles/Tips-for-Avoiding-Coronavi-by-Meryl-Ann-Butler-Corona-Virus-Coronavirus-Covid-19_Johns-Hopkins_Physicians-Response-To-Coronavirus_Soap-200329-113.html

This was the meme:

YOU SHOULD READ THIS INFORMATION From John Hopkins Hospital:

* The virus is not a living organism, but a protein molecule (DNA) covered by a protective layer of lipid (fat), which, when absorbed by the cells of the ocular, nasal or buccal mucosa, changes their genetic code. (mutation) and convert them into aggressor and multiplier cells.

* Since the virus is not a living organism but a protein molecule, it is not killed, but decays on its own. The disintegration time depends on the temperature, humidity and type of material where it lies.

* The virus is very fragile; the only thing that protects it is a thin outer layer of fat. That is why any soap or detergent is the best remedy, because the foam CUTS the FAT (that is why you have to rub so much: for 20 seconds or more, to make a lot of foam).

By dissolving the fat layer, the protein molecule disperses and breaks down on its own.

* HEAT melts fat; this is why it is so good to use water above 25 degrees Celsius for washing hands, clothes and everything. In addition, hot water makes more foam and that makes it even more useful.

* Alcohol or any mixture with alcohol over 65% DISSOLVES ANY FAT, especially the external lipid layer of the virus.

* Any mix with 1 part bleach and 5 parts water directly dissolves the protein, breaks it down from the inside.

* Oxygenated water helps long after soap, alcohol and chlorine, because peroxide dissolves the virus protein, but you have to use it pure and it hurts your skin.

* NO BACTERICIDE OR ANTIBIOTIC SERVES. The virus is not a living organism like bacteria; antibodies cannot kill what is not alive.

* NEVER shake used or unused clothing, sheets or cloth. While it is glued to a porous surface, it is very inert and disintegrates only

-between 3 hours (fabric and porous),

-4 hours (copper and wood)

-24 hours (cardboard),

- 42 hours (metal) and

-72 hours (plastic).

But if you shake it or use a feather duster, the virus molecules float in the air for up to 3 hours, and can lodge in your nose.

* The virus molecules remain very stable in external cold, or artificial as air conditioners in houses and cars.

They also need moisture to stay stable, and especially darkness. Therefore, dehumidified, dry, warm and bright environments will degrade it faster.

* UV LIGHT on any object that may contain it breaks down the virus protein. For example, to disinfect and reuse a mask is perfect. Be careful, it also breaks down collagen (which is protein) in the skin.

* The virus CANNOT go through healthy skin.

* Vinegar is NOT useful because it does not break down the protective layer of fat.

* NO SPIRITS, NOR VODKA, serve. The strongest vodka is 40% alcohol, and you need 65%.

* LISTERINE IF IT SERVES! It is 65% alcohol.

* The more confined the space, the more concentration of the virus there can be. The more open or naturally ventilated, the less.

* You have to wash your hands before and after touching mucosa, food, locks, knobs, switches, remote control, cell phone, watches, computers, desks, TV, etc. And when using the bathroom.

* You have to HUMIDIFY HANDS DRY from so much washing them, because the molecules can hide in the micro cracks. The thicker the moisturizer, the better.

* Also keep your NAILS SHORT so that the virus does not hide there.

-JOHNS HOPKINS HOSPITAL The Johns Hopkins Hospital is ranked among nation's best

Saturday, March 28, 2020

Make leaf blowing illegal

Why I think leaf blowing is particularly dangerous for COVID-19 spread

When we talk about the survival time of viruses on surfaces, we’ve been seeing research about man-made services: copper, cardboard, plastic, steel.

The ground is a much more complex environment. There are bits and pieces of things. There’s moisture. There are nutrients. It would require a serious scientific study to determine what sorts of ground environments are best for survival of the virus.

There was an article a couple of weeks ago in Scientific American where they described a Chinese scientist who discovered a virus and 97% similar to this one in a bat cave in China in 2013. From this, most scientists have concluded that the virus did originate in a bat cave. Bat caves have complex environments, as well.

Consider the ground, in a cool, moist, spring environment. The underside of a small leaf bit could be an ideal place for a virus to hide from the disinfecting ultraviolet rays of the sun. Using a high-powered blower to rocket that leaf bit into the air could be a very dangerous way of aerosolizing the virus.

This is a pandemic. We know people have been coughing and spitting all over the place. The virus could be literally anywhere.

I doubt that there has been time to do a careful scientific study of the effects of leaf blowing right now. We cannot rely on previous studies of the effects of leaf blowing to understand the consequences of this activity on covid-19.

I call upon the state of New York to declare leaf blowing Illegal. Also power mowers without bags should be illegal.



Sunday, March 22, 2020

Argument for requiring masks -- even if they're DIY


There is now an official peer reviewed Study stating the novel coronavirus is viable in the air for up to three hours.


This means that, if you walk past where someone recently exhaled, you could inhale viable virus.  This could happen even if you're six feet apart.  You can normally walk six feet in 2-3 seconds, which is not long enough for the virus to fall to the ground.

I'm upset that we've been getting this advice to not wear masks.  This advice has been extremely irresponsible and not founded in science. 

The following article on DIY masks states that even ordinary tee shirt fabric would filter out 50% of viruses, which is better than nothing.  We have people get flu shots that are less effective than that.


By contrast, in the case of colds and flu, hand washing has been found to be only about 20% effective in preventing spread. It's more effective in preventing spread of digestive viruses.


This extreme emphasis on hand washing and no masks is putting everyone at risk.

In China, where they have succeeded in slowing spread of the virus, everyone is required to wear a mask.

I believe we should require everyone to wear a mask outside their homes -- and, given that there is a shortage of disposable masks, we should be supplying everyone with washable, reusable masks.  My understanding is that various clothing factories are retooling to make such masks. They might not be as good as an N95 mask, but they are better than nothing.

Here are some more instructions for making your own mask








And here’s a cite that seems to undermine the whole hand washing thing entirely.  The CDC thinks that the virus is primarily transmitted by droplets of saliva or mucus landing in the mouth, nose, or eyes. It has not been proven that you can get it from surfaces.

https://www.cdc.gov/coronavirus/2019-ncov/prepare/transmission.html

-----------

finally an article that agrees with me https://www.washingtonpost.com/outlook/2020/03/28/masks-all-coronavirus/

Here is the author's twitter account.  He is a kindred spirit.  I appreciate him
https://twitter.com/jeremyphoward

Here's a Korean expert recommending masks


-----------

Here's a website claiming that vacuum cleaner bags do not contain fiberglass

https://www.vacuumcleanermarket.com/news/do-vacuum-bags-contain-fiberglass/

Here's an article about how masks and handwashing do not prevent "transmission" in flu
https://wwwnc.cdc.gov/eid/article/26/5/19-0994_article

I feel that the above article is misworded.  These measures do not protect against infection.  However they do protect against transmission.